Updated review of treatment guidelines for schizophrenia in a specialized institute: focus on pharmacological and psychosocial therapies

Revilla-Zúñiga J.; Sagástegui-Soto A.; Carazas-Vera M.; Saavedra-Castillo A. · Revista de Neuro-Psiquiatria (2025) · DOI: 10.20453/rnp.v88i2.6248

Resumen

Schizophrenia is a complex and heterogeneous mental disorder. This article presents an updated review of the main pharmacological and psychosocial recommendations for the management of adult patients withschizophrenia in a level III-2 healthcare facility in Peru. Non-systematic review of the literature recorded on PubMed/MEDLINE, Scopus, EMBASE, Cochrane Library, ScienceDirect, and Google Scholar. The management of schizophrenia in adults requires a pharmacological approach with antipsychotics, which can be administered through oral, rapid-acting or long-acting parenteral routes. Before starting and during the treatment, periodic baseline examinations are recommended. The use of scales also allows the evaluation of antipsychotic response.Regularassessmentofadverse/secondaryevents,suchasextrapyramidal symptoms, is recommended. In treatment-resistant schizophrenia, the use of clozapine is recommended. From the psychotherapeutic perspective, individual and group cognitive-behavioural therapy approaches stand out. The clinical management of schizophrenia involves an individualized pharmacological modality, and a non-pharmacological approach that involves both the patient and his/her social context. © Los autores © Revista de Neuro-Psiquiatría.

Instituciones: Universidad Peruana Cayetano Heredia