Sister Mary Joseph's nodule in papillary serous ovarian cancer. Case report and literature review

Lara E.; Díaz D.; Rezic M.; Hoegl J.; González H. · Revista de Obstetricia y Ginecologia de Venezuela (2020)

Resumen

Sister Mary Joseph's nodule refers to a metastatic lesion in the umbilical region; it is a rare entity that occurs in 1 to 3% of patients with intra-abdominal and / or pelvic neoplasia. We describe a case concerning to an umbilical metastasis of an ovarian papillary serous adenocarcinoma, the umbilical lesion being the only sign of metastatic disease. The patient is a 51 years old female, who has been consulting for an umbilical lesion since August 2017, which is resected in a foreign center and in view of results that report papillary serous cystadenocarcinoma, is referred to. After carrying out the extension studies, she is taken to the operating table. Performing primary debulking (type II radical oophorectomy), considering an optimal surgery with favorable postoperative evolution. This sign is a rare entity of cutaneous metastasis and requires us to suspect advanced malignant pathology. It is necessary to make a histological differential diagnosis with primary (benign and neoplastic) and metastatic lesions.