Role of the intraoperative study in decision-making in urological oncology

Astigueta-Pérez J.; Abad-Licham M.; Gonzáles-Saravia J. · Gaceta Mexicana de Oncologia (2024) · DOI: 10.24875/j.gamo.m23000259

Resumen

Background: The intraoperative study is a main diagnostic procedure for decision-making in urological oncology. There are few publications, and they are mainly related to the evaluation of surgical margins. Objective: To determine the role of the intraoperative study (IS) in patients with uro-oncological neoplasms. Method: This was an analytical, observational, cross-sectional, and diagnostic test study. The anatomical-pathological results of patients treated in the Urology Service of the Instituto Regional de Enfermedades Neoplásicas Norte were evaluated, in the period 2010–2019, in which the result of the IS was compared with that obtained in the histological study (HS) processed in paraffin (gold standard). Results: Sixty-six EIO with their respective HE were included, 16 (24%) patients were females and 50 (76%) males. The average age was 52.1, with a range between 17 and 84 years. Of the total EIO, 37 (56.1%) were positive for malignant neoplasm, 28 (42.4%) were negative, and 1 (1.5%) could not be defined. In HE, the diagnosis was confirmed in 62 cases (95.4%) and discrepancies were found in 3 (4.6%). The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of the EIO were 94.7, 96.3, 97.3, 92.9, and 95.4%, respectively; likewise, the positive and negative likelihood ratios were 25.6 and 0.05. Conclusion: EIO in uro-oncology is useful and highly reliable in decision-making during surgery.

Instituciones: Universidad Privada Antenor Orrego