Risk factors for poor functional outcome in patients hospitalized for spontaneous intracerebral hemorrhage in a reference hospital from Piura

Nathaly T.-C.M.; Miguel V.A.; Diego U.-P. · Revista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo (2025) · DOI: 10.35434/rcmhnaaa.2025.181.2665

Resumen

Objective: To evaluate the risk factors for poor functional prognosis in patients hospitalized for spontaneous intracerebral hemorrhage. Material and Methods: A retrospective cohort study was carried out where 68 patients with a diagnosis of intracerebral hemorrhage were included in a reference hospital in Peru from 2020 to 2022. The clinical history was used, which included demographic, clinical, laboratory and imaging data. Associations between qualitative variables and the incidence of poor functional outcomes and mortality were established using Pearson's chi-square test. Crude relative risks (RRc) with 95% confidence intervals were calculated, and a Poisson linear model with a logarithmic link function and robust variances was applied. Results: 64.7% experienced poor functional outcome, the associated factors were: previous cerebrovascular disease, Glasgow Coma Scale on admission from 3 to 8, leukocyte level, INR, early neurological deterioration, and in-hospital complications. 38.2% of patients died where it was associated with: Glasgow Coma Scale on admission from 3 to 8, early and late neurological deterioration, elevated levels of leukocytes, INR, elevated glucose and in-hospital complications. Conclusion: This cohort is the first regional study in Peru of patients with spontaneous intracerebral hemorrhage, in which a high rate of poor functional outcome and mortality is reported. These results may help us to perform more intensive monitoring in the group of patients with a higher risk of worse outcomes.

Instituciones: Universidad Científica del Sur; Universidad César Vallejo