Rendu-Osler-Weber Syndrome with Gastrointestinal, Hepatic, and Pancreatic Involvement

Huanay-Martínez D.A.; Chávez S.; Bellido-Caparó. Á. · Revista Colombiana de Gastroenterologia (2025) · DOI: 10.22516/25007440.1216

Resumen

Rendu-Osler-Weber syndrome (ROWS) is characterized by the development of aberrant vascular structures such as dilated microvessels and arteriovenous malformations (AVMs) in the skin, gastrointestinal (GI) tract, lungs, liver, brain, and less commonly in the kidneys and pancreas. Complications include strokes, septic emboli, mesenteric ischemia, portal hypertension, and high-output cardiac failure. We report the case of a 52-year-old male patient with a history of recurrent epistaxis since adolescence and a family history of the same condition, who presented with symptoms of severe iron deficiency anemia. Endoscopic and radiologic studies confirmed the diagnosis of Rendu-Osler-Weber syndrome with hepatic and pancreatic involvement. The patient was referred for argon plasma coagulation therapy.

Instituciones: Universidad Peruana Cayetano Heredia