Proteinosis alveolar pulmonar: El reto diagnóstico en una rara enfermedad pulmonar. Descripción de un caso clínico

Casaverde I.J.; Escalante P.T.; Azañero-Haro J. · Gaceta Medica Boliviana (2025) · DOI: 10.47993/gmb.v48i1.845

Resumen

Pulmonary alveolar proteinosis is a rare lung condition characterized by the accumulation of surfactant due to impaired regulation. This case involves a 41-year-old female patient who was admitted to the hospital with worsening dyspnea at rest over a period of 11 months, along with a persistent dry cough. Chest tomography showed thickening of the intra and interlobular pulmonary interstitium, ground-glass opacities bilateral. Bronchoscopy yielded turbid, milky fluid. Pulmonary biopsy validated the diagnosis of pulmonary alveolar proteinosis. The patient showed clinical improvement during her hospital stay. This case emphasizes the need to consider uncommon conditions, like pulmonary alveolar proteinosis, in the differential diagnosis of patients presenting with respiratory distress and pulmonary infiltrates.

Instituciones: Universidad Científica del Sur