Primary pancreatic lymphoma: a rare pancreatic neoplasm

Beltrán-Gárate B.; Alburqueque-Melgarejo J.; Vela-Ruiz J.M.; Ávila M.P.-Q.; Montenegro E.G.M.C. · Revista Cubana de Medicina Militar (2025)

Resumen

Introduction: Primary pancreatic lymphoma is a rare entity that represents approximately less than 0.5% of all pancreatic neoplasms. Objective: To illustrate the diagnostic complexity of primary pancreatic lymphoma. Case Report: A 73-year-old male patient with no history of comorbidities, surgical interventions, or drug use presented with a clinical picture characterized by jaundice and intermittent abdominal pain. A CT scan revealed a solid lesion in the head of the pancreas and the ampullary region, encasing the hepatic artery and partially the gastroduodenal artery. A biopsy confirmed the presence of a B-cell non-Hodgkin lymphoma. Chemotherapy was effective, and the patient is currently in recovery. Conclusions: Primary pancreatic lymphoma should be considered as a differential diagnosis for pancreatic masses, especially when the clinical presentation is nonspecific, since its early detection allows for less invasive treatment with a better prognosis than pancreatic adenocarcinoma.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad Científica del Sur; Universidad de San Martín de Porres; Universidad Privada Antenor Orrego