Premalignant lesions and cervical cancer unrelated to human papillomavirus

Taxa L. · Revista Peruana de Ginecologia y Obstetricia (2024) · DOI: 10.31403/rpgo.v70i2694

Resumen

Cervical cancer is the second most common malignancy in Peruvian women. The new WHO classification divides cervical epithelial neoplasms according to the presence or absence of human papillomavirus (HPV) for both squamous and glandular types. Much has been studied on HPV-related cervical cancer and little in HPV-negative cervical cancer, which, although representing a minority group, is of different behavior and worse prognosis. This review represents an overview of this pathological with emphasis on molecular aspects. Undoubtedly, with the research of this pathology group and mainly molecular development, more specific treatments are expected.

Instituciones: Universidad de San Martín de Porres