Pregnancy outcomes among women with and without COVID-19 in a national level III hospital in Peru

Carranza-Asmat C.; Espinola-Sánchez M.; Guevara-Ríos E.; Velásquez-Vásquez C.; Ayala-Peralta F.; Meza-Santibáñez L.; Gonzales-Carrillo O.; Díaz-Villar J.; Racchumí-Vela A.; Arango-Ochante P.; Saldaña-Díaz C.; Minchon-Medina C. · Revista Chilena de Obstetricia y Ginecologia (2022) · DOI: 10.24875/rechog.21000002

Resumen

Objective: To compare pregnancy outcomes among women with and without COVID-19 infection attended in a national level III hospital in Peru. Method: Observational, retrospective and comparative study. RT-PCR positive pregnant women participated in a 1:1 ratio with negative RT-PCR, and 1:2 with pregnant women of 2019. Maternal and perinatal information was collected. Fisher’s exact test was used with a significance level of 0.05 and prevalence ratios (PR) with their confidence interval of 95% (CI95%). Results: 51 pregnant women with positive RT-PCR, 51 with negative RT-PCR and 102 pregnant women in 2019 participated. RT-PCR test were associated to preterm delivery (p < 0.05). The PR for preterm delivery in women with positive RT-PCR compared to pregnant women in 2019 was 3.14 (CI95%: 1.29-7.64); and compared to women with negative RT-PCR was 4.0 (CI95%: 1.13-14.17). Conclusions: The study’s findings suggest the existence of an association between maternal COVID-19 and preterm birth. However, more studies are required to analyze the role of maternal factors.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad Nacional de Trujillo; Universidad Privada del Norte