OMERACT 2023 Systemic Lupus Erythematosus Special Interest Group: Winnowing and Binning Preliminary Candidate Domains for the Core Outcome Set

Nielsen W.; Strand V.; Simon L.S.; Parodis I.; Kim A.H.J.; Desai M.; Enman Y.; Wallace D.; Chaichian Y.; Navarra S.; Aranow C.; MacKay M.; Trotter K.; Tayer-Shifman O.E.; Duarte-Garcia A.; Shan Tam L.; Ugarte-Gil M.F.; PonsEstel G.J.; Reynolds J.A.; Nikpour M.; Hoi A.; Romero-Diaz J.; Papachristos D.; Aggarwal A.; Mok C.C.; Fujio K.; Ramsey-Goldman R.; Howe A.; Kia B.N.; Bonilla D.; Thumboo J.; Mosca M.; Aringer M.; Johnson S.R.; Drucker A.M.; Morand E.; Bruce I.; Touma Z. · Seminars in Arthritis and Rheumatism (2024) · DOI: 10.1016/j.semarthrit.2024.152380

Resumen

Background: The Outcome Measures in Rheumatology (OMERACT) Systemic Lupus Erythematosus (SLE) Working Group held a Special Interest Group (SIG) at the OMERACT 2023 conference in Colorado Springs where SLE collaborators reviewed domain sub-themes generated through qualitative research and literature review. Objective: The objective of the SIG and the subsequent meetings of the SLE Working Group was to begin the winnowing and binning of candidate domain sub-themes into a preliminary list of candidate domains that will proceed to the consensus Delphi exercise for the SLE COS. Methods: Four breakout groups at the SLE SIG in Colorado Springs winnowed and binned 132 domain sub-themes into candidate domains, which was continued with a series of virtual meetings by an advisory group of SLE patient research partners (PRPs), members of the OMERACT SLE Working Group Steering Committee, and other collaborators. Results: The 132 domain sub-themes were reduced to a preliminary list of 20 candidate domains based on their clinical and research relevance for clinical trials and research studies. Conclusion: A meaningful and substantial winnowing and binning of candidate domains for the SLE COS was achieved resulting in a preliminary list of 20 candidate domains.

Instituciones: Universidad Científica del Sur