Neutrophil lymphocyte index as a factor associated with mortality in patients with severe craniocerebral trauma

Vásquez-Tirado G.A.; Roldan-Mori N.E.; Roldan-Mori M.M.; Alva-Medina D.J.; Quispe-Castañeda C.V.; Meregildo-Rodríguez E.D.; Segura-Plasencia N.M.; Arbayza-Avalos Y.K.; Rodríguez-Chávez L.Á.; Romero-Díaz M.Y.; Cabanillas-López J.; Alva-Guarniz H.; Torres-García S.Y.; Roldan-Mori F. · Medicina Clinica Practica (2024) · DOI: 10.1016/j.mcpsp.2023.100403

Resumen

Objective: To determine if the neutrophil-lymphocyte index is a factor associated with mortality in patients with severe traumatic brain injury. In order to establish a rapid marker of unfavorable evolution and adverse outcomes in these patients. Material and methods: The clinical history of 238 patients with severe traumatic brain injury treated in the Intensive Care Unit of the Trujillo Regional Teaching Hospital during the period 2016-2022 was reviewed. Results: The neutrophil-lymphocyte index did not show a significant association with mortality (HRc 1.97 95% CI 0.82-4.72) (p > 0.5). The bivariate and multivariate analysis where the intervention of other variables was associated, determined that anisocoria increased the risk of death by 4 times (HRc 4.1; IC95%; 1.86-9.04) (p < 0.001), shock increased the risk of death by 6 times. Death (HRc 6.64; 95%; CI 2.49-17.73) (p < 0.001), and hypernatremia doubled the risk of death (HRc 2.24; 95%; CI 1.005-4.82) (p < 0.04). Conclusions: It was found that anisocoria, shock, hospital stay and Glasgow coma scale at admission are independent predictors of mortality.

Instituciones: Universidad Privada Antenor Orrego