NeoArgosTools: A Flowchart Pipeline Tool for Neoantigen Detection from Single Nucleotide Variants

Machaca V.; Lopez D.; Mamani J.; Ramos S.; Túpac Y. · Smart Innovation, Systems and Technologies (2026) · DOI: 10.1007/978-981-95-1361-1_10

Resumen

Cancer immunotherapy offers a promising option to conventional cancer therapies, in this field, neoantigen detection is a rapidly evolving field; however, as it requires multiple bioinformatics stages, such as quality control, alignment, variant calling, annotation, and neoantigen prioritization. Each stage depends on specific software tools, which can create technical and compatibility challenges, often requiring significant expertise to integrate and manage. To address these challenges, we introduce NeoArgosTools, a novel flowchart-based platform, with an intuitive graphical interface, designed to simplify and streamline neoantigen detection pipelines in cancer immunotherapy research. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2026.

Instituciones: Universidad La Salle; Universidad Católica San Pablo