Nanoencapsulation of Phenolic Extracts from Native Potato Clones (Solanum tuberosum spp. andigena) by Spray Drying

Ligarda-Samanez C.A.; Choque-Quispe D.; Moscoso-Moscoso E.; Palomino-Rincón H.; Taipe-Pardo F.; Landa J.P.A.; Arévalo-Quijano J.C.; Muñoz-Saenz J.C.; Quispe-Quezada U.R.; Huamán-Carrión M.L.; Gutiérrez-Gómez E.; Sucari-León R.; Luciano-Alipio R.; Muñoz-Saenz J.M.; Guzmán Gutiérrez R.J. · Molecules (2023) · DOI: 10.3390/molecules28134961

Resumen

Native potato clones grown in Peru contain bioactive compounds beneficial to human health. This study aimed to optimize the spray-drying nanoencapsulation of native potato phenolic extracts utilizing a central composite design and response surface methodology, obtaining the optimal treatment to an inlet temperature of 120 °C and an airflow of 141 L/h in the nano spray dryer B-90, which allowed maximizing the yield of encapsulation, antioxidant capacity (DPPH), encapsulation efficiency (EE), total phenolic compounds, and total flavonoids; on the other hand, it allowed minimizing hygroscopicity, water activity (Aw), and moisture. Instrumental characterization of the nanocapsules was also carried out, observing a gain in lightness, reddening of the color, and spherical nanoparticles of heterogeneous size (133.09–165.13 nm) with a negative ζ potential. Thermal, infrared, and morphological analyses confirmed the encapsulation of the core in the wall materials. Furthermore, an in vitro release study of phenolic compounds in an aqueous solution achieved a maximum value of 9.86 mg GAE/g after 12 h. Finally, the obtained nanocapsules could be used in the food and pharmaceutical industry.

Instituciones: Universidad Nacional José María Arguedas; Universidad Nacional Autónoma de Huanta; Universidad Nacional Autónoma Altoandina de Tarma