Multi-response optimization of anti-GnRH immunocastration on growth performance and meat quality in weaned male guinea pigs

Ninahuanca J.; Castro-Carhuas J.; Garcia-Olarte E.; Quispe-Eulogio C.; Ancco-Gomez E.; Rojas J.L.S. · Veterinary Integrative Sciences (2026) · DOI: 10.12982/vis.2026.081

Resumen

This study evaluated the effects of different doses of an anti-GnRH immunocastrator on growth performance and meat quality in weaned male guinea pigs using a multi-response optimization approach. A total of 40 animals were randomly assigned to four treatments: one control group and three Bopriva® doses (0.20, 0.30, and 0.40 mL/animal), administered in two subcutaneous applications. Direct and derived productive traits, as well as physicochemical and color-related meat quality variables, were recorded. Statistical analysis included descriptive statistics, ANOVA, robust complementary tests, multivariate analysis of variance, principal component analysis, and the construction of a global decision index I(α) = αQ + (1 − α)Q, where P represents the productive component and Q represents the meat quality component. The results showed that the intermediate dose achieved the best performance in growth and carcass weight, whereas the highest dose exhibited the best integrated meat-quality response and the highest global index value under a balanced scenario. The crossover point α∗ = 0.522 indicated that the optimal recommendation depended on the relative weight assigned to productivity and quality. It is concluded that T3 represents the best alternative when productive performance is prioritized, whereas T4 is more suitable when the main objective is to optimize meat quality and the overall balanced response.

Instituciones: Universidad Peruana Los Andes; Universidad Nacional del Centro del Perú