Molecular Mechanisms and Respiratory, Cardiovascular and Neurological Clinical Manifestations of Post-acute COVID-19 Syndrome

Saravia-Bartra M.; Alvarado Á.; Pariona-Llanos R.; Valderrama-Wong M.; Ignacio-Conchoy F.; Cazorla-Saravia P.; Cazorla P.; Losno-García R. · Revista Cubana de Farmacia (2023)

Resumen

Introduction: Post-acute COVID-19 syndrome is a set of signs and symptoms that develop during or after clearance of SARS-CoV-2 virus and continue for more than 12 weeks and are not explained by an alternative diagnosis. Objective: To describe the molecular mechanism involved in respiratory, cardiovascular and neurological dysfunctions and their clinical manifestations. Methods: A literature review of articles published from 2020 to 2022 was performed. PubMed/Medline, SciELO and Google Scholar databases were consulted, various Spanish and English language descriptors were used. Conclusions: Patients could present COVID-19 post-acute syndrome six months after recovery. The most relevant clinical manifestations are persistent respiratory dysfunction, cardiovascular and neurological dysfunction.

Instituciones: Universidad San Ignacio de Loyola