Meta-analysis of predictors of healthcare-associated Clostridioides difficile infection

Fajnzylber J.; Patterson W.M.; Nero N.; Hernandez A.V.; Deshpande A. · Antimicrobial Stewardship and Healthcare Epidemiology (2024) · DOI: 10.1017/ash.2024.413

Resumen

Our systematic review and meta-analysis of 40 studies (n = 3,905,559) identified gastric acid suppressants, recent hospitalization, antibiotic exposure, and certain comorbidities as independent predictors of healthcare-associated Clostridioides difficile infection (HA-CDI) among adult inpatients. Targeted antibiotic stewardship and judicious use of gastric acid suppressants can reduce the incidence of HA-CDI. © The Author(s), 2024.

Instituciones: Universidad San Ignacio de Loyola