Mechanical power as a predictor of mortality in critical ill patients with acute respiratory distress syndrome by Covid-19 in the intensive care unit

Vásquez-Tirado G.A.; del Carmen Cuadra Campos M.; Meregildo-Rodriguez E.D.; Segura-Plasencia N.M.; Arbayza-Ávalos Y.K.; Quispe-Castañeda C.V. · Boletin de Malariologia y Salud Ambiental (2022) · DOI: 10.52808/bmsa.7e6.622.016

Resumen

Background: Invasive mechanical ventilation as a therapeutic strategy is not without complications. It is imperative to have protective ventilation parameters in those patients who are subjected to it. We aim to demonstrate whether mechanical power as a ventilatory parameter has prognostic validity for mortality in critically ill patients with prolonged invasive mechanical ventilation. Material and Methods: An analytical cross-sectional study was carried out of critically ill patients on prolonged invasive mechanical ventilation due to Acute Respiratory Distress Syndrome due to COVID-19 who were admitted to the Intensive Care Unit of the Hospital Regional de Trujillo during the March 2020 to March 2021 period. Results: Mechanical power, as a ventilatory parameter, is associated with mortality (RPa 1.061; 95% CI 1.037-1.085; p = 0.00) as well as plateau pressure, and driving pressure and static compliance are protective factors for mortality. Mechanical power as a ventilatory parameter has prognostic validity for mortality in critically ill patients with invasive mechanical ventilation due to severe acute respiratory distress syndrome due to COVID-19.

Instituciones: Universidad Privada Antenor Orrego; Universidad César Vallejo