Jejunal gastrointestinal stromal tumor: A report of a challenging diagnosis and a life-threatening emergency

Tenazoa-Villalobos J.R.; Yan-Quiroz E.F.; Burgos-García O.M.V.; Llerena-Cobián G. · International Journal of Gastrointestinal Intervention (2026) · DOI: 10.18528/ijgii250026

Resumen

Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms that may occur anywhere along the digestive tract; approximately 10% arise in the jejunum. Patients typically present with abdominal pain, although symptoms can include bowel obstruction or gastrointestinal bleeding. Bleeding arises from mucosal ulceration and necrosis due to tumor mass effect. GISTs are classified by size, with some current guidelines recommending conservative management for lesions smaller than 2 cm. In this report, we present two cases. The first case involved a 37-year-old woman with abdominal pain and anemia who underwent surgery and was diagnosed with locally advanced primary jejunal GIST, pathological stage pT4N0M0 (Stage II), and responded well to imatinib. The second case involved a 40-year-old man with massive gastrointestinal bleeding from a jejunal GIST who underwent emergency surgery and had an uncomplicated postoperative course. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Instituciones: Universidad Privada Antenor Orrego