INHIBITORY EFFECT OF ALLIUM SATIVUM AGAINST PSEUDOMONAS AERUGINOSA AND MULTI-RESISTANT ACINETOBACTER BAUMANNII

Campos-Monteza C.; López-Ugarte L.; Iglesias-Osores S.; Moreno-Mantilla M. · Medicina Naturista (2022)

Resumen

The objective of this research was to determine the in vitro inhibitory effect of the aqueous extract of Allium sativum L. “garlic” at concentrations of 100, 200. 300, 400, 500 mg / ml against Pseudomonas aeruginosa and Acinetobacter baumannii isolated from the Regional Hospital of Lambayeque, minimum inhibitory concentration and minimum bactericidal concentration. Using as methods: diffusion of modified Kirby Bauer, tube macrodilution technique and minimum bactericidal concentration according to Abadie et al. The aqueous extract of Allium sativum L. “garlic” showed significant in vitro inhibitory effect on Acinetobacter baumannii multidrug with an average halo of inhibition of 22.02 mm and mild in Pseudomonas aeruginosa multugistant with a mean halo of inhibition of 7.28 mm. The minimum inhibitory concentration (MIC) of the aqueous extract of Allium sativum L. “garlic” on multi-resistant strains of Acinetobacter baumannii was determined to be 1.56 mg / ml, while in Pseudomonas aeruginosa 12.25 mg / ml (strains 2, 3) and 25 mg / ml (strain 1). It was determined that the aqueous extract of Allium sativum L. had lower minimum bactericidal concentration (CMB) on Acinetobacter baumannii multi-resistant strain 3 equals to 1.56 mg / ml and higher in Pseudomonas aeruginosa multi-resistant strain 3 equal to 50 mg / ml.

Instituciones: Universidad Nacional Pedro Ruiz Gallo