In vitro antifungal activity comparation of 2% chlorhexidine gluconate and 5,25% sodium hypochlorite against Candida albicans

Alvarez-Chupillón H.A.; Portocarrero-Mondragón J.P.; Pardo-Aldave K. · Avances en Odontoestomatologia (2022)

Resumen

Background: the presence of fungal species is evident in the dental root canal system. Aim: to compare the in vitro antifungal activity of two solutions against Candida albicans. Methos: In vitro experiment. 90 samples were isolated by swabbing the buccal mucosa from patients with sub-prosthetic stomatitis, distributed in two groups: 45 with 5.25% Na OCl discs and the other 45 with 2% CHX discs. Shapiro Wilk test, p> 0.05 and Levene test, p> 0.05. Student’s t was used for comparison. Results: 2% chlorhexidine gluconate and 5.25% sodium hypochlorite antifungal activity with mean in-hibition halos of 24.6 mm and 25.2 mm, respectively. Conclusion: There are no significant differences between the two agents studied.

Instituciones: Universidad de San Martín de Porres; Universidad Señor de Sipán