Hyperprolactinemic Galactorrhea Following Pneumonectomy for Tuberculosis Sequelae

Segura Núñez P.; Monge Espinoza F.; Orihuela Baldeón M.; Piscoche Rodríguez C.E.; Paucar Baldeón F.S.; Riveros-Mendoza N.B.; Vargas M. · Revista Cubana de Medicina Tropical (2026)

Resumen

Introduction: Hyperprolactinemia is a neuroendocrine disorder characterized by elevated serum prolactin levels, with physiological, pharmacological, or pathological etiologies. Its manifestations include galactorrhea, sexual dysfunction, and infertility. Objective: To describe a case of hyperprolactinemia secondary to chest trauma in a patient with a history of pneumonectomy due to pulmonary tuberculosis sequelae. Clinical case report: A 33-year-old woman with a history of pneumonectomy for pulmonary tuberculosis developed galactorrhea and hyperprolactinemia, with normal thyroid and renal function. Pituitary MRI showed no structural lesions or tumors. After ruling out common causes, a diagnosis of hyperprolactinemia secondary to chest trauma was established. Its pathophysiology was attributed to abnormal stimulation of the intercostal and upper thoracic nerves. Conclusions: This case highlights the importance of considering a history of chest trauma in patients with hyperprolactinemia of no apparent cause, as well as the need for an interdisciplinary clinical approach for its proper diagnosis and management. Esta obra está bajo una licencia: https://creativecomons.org/licenses/by-nc/4.0/deed.es_ES

Instituciones: Universidad Ricardo Palma; Universidad Tecnológica del Perú