Histological effect of fluoride varnishes on teeth with caries in the white spot phase: An in vitro study

Gutiérrez-Ilave M.M.; Ríos-León R.D.P.; Castro-Rodríguez A.; Calixto-Cotos M.R. · Journal of Clinical and Experimental Dentistry (2025) · DOI: 10.4317/jced.62010

Resumen

Background: The aim of this study was to compare the histological remineralization effects of two fluoride varnishes on artificially produced caries lesions in young permanent teeth. Material and Methods: Twenty longitudinal sections of premolars with artificially produced white spot lesions and evaluated with a polarised light microscope. The sample consisted of 20 tooth fragments, which were divided and assigned to two groups: The first group with application of Clinpro TM White Varnish (20 tooth sections) and the second, with MI Varnish TM (20 tooth sections) subjected for 6 days to conditions similar to the oral cavity. The sections were then re-evaluated by calculating the lesion depth and remineralization area (Image J software). Student’ s t-test was used to analyse the data. Results: MI Varnish TM fluoride varnish achieved a greater remineralization area than Clinpro TM White Varnish (838042.6±140359.3 μm2 and 678313.8±137265.7μm2, respectively), with a statistically significant difference (p<0.05). Conclusions: MI Varnish TM had a better effect than Clinpro TM White Varnish in remineralizing lesions, in vitro, in the enamel of young permanent teeth with caries in the white-stained phase. © Medicina Oral S. L. C.I.F. B 96689336 - eISSN: 1989–5488

Instituciones: Universidad Nacional Mayor de San Marcos