Heterologous prime-boost vaccination against COVID-19: is it safe and reliable?

Choudhary O.P.; Priyanka; Ahmed J.Q.; Mohammed T.A.; Singh I.; Rodriguez-Morales A.J. · Human Vaccines and Immunotherapeutics (2021) · DOI: 10.1080/21645515.2021.2007015

Resumen

Throughout the globe, many nations are struggling to cope with the consecutive waves of the COVID-19. Several vaccines have been employed to overcome this ongoing pandemic and are available as single and double-dose inoculations; however, homologous vaccine efficacy is being reconsidered due to the rapidly emerging SARS-CoV-2 variants. Many studies have been conducted on the heterologous prime-boost vaccine regimens and have shown good efficacy results against COVID-19. This article aims to highlight the safety and reliability of heterologous prime-boost vaccination against COVID-19. We have also made some recommendations towards using these combinations of vaccines for the global mitigation of the subsequent waves of COVID-19.

Instituciones: Universidad Científica del Sur