Hepatoprotective effect of Nostoc commune (cushuro) consumption against damage induced by sucrose-rich diets in mice

Bejarano-Carhuancho J.I.M.; Huamaní-Zavaleta W.N.; Huamán-Gutiérrez O.G. · Nutricion Clinica y Dietetica Hospitalaria (2024) · DOI: 10.12873/441bejarano

Resumen

Objective: To evaluate the hepatoprotective effect of the consumption of Nostoc commune (cushuro) against the damage induced by diets rich in sucrose in mice. Methods: The study had a quantitative, pure experimental approach with control group and post test. Twenty-eight male mice with an average weight of 30 ± 6.2 g and sprayed with Nostoc commune were used. The animals were divided into four groups and received the following diets for 50 days: Group I: diet A (sucrose 10%), group II: diet B (sucrose 36.5%), group III: diet C (sucrose 36.5 % + cushuro 1%) and group IV: diet D (sucrose 36.5% + cushuro 3%). Finally, the liver was extracted and biochemical and histological analyzes were performed. The ANOVA statistic was applied for symmetric data and Kruskall-Wallis for asymmetric data. Results: In groups III and IV it was observed that the triglyceride levels (p<0.05) decreased and a better conservation at the histological level was also observed. Conclusion: The consumption of Nostoc commune (cushuro) has a hepatoprotective effect expressed in the reduction of triglycerides and conservation at the histological level against the damage induced by diets rich in sucrose in mice.

Instituciones: Universidad Nacional Mayor de San Marcos