Granulomatosis with polyangiitis and Kartagener’s syndrome

Paredes M.; Hidalgo J. · Anales de la Facultad de Medicina (2024) · DOI: 10.15381/anales.v85i2.27009

Resumen

We present a 42-year-old woman with a 1-year history of chronic rhinosinusitis, left facial palsy, bilateral sensorineural hearing loss, and bilateral necrotizing scleritis. Analytics revealed, elevated C-reactive protein and positive anti-proteinase 3. Tomography showed varicose and cystic bronchiectasis in both lungs and situs inversus totalis. It was concluded that the clinical assessment was compatible with Granulomatosis with polyangiitis in a patient with Kartagener’s Syndrome. She received immunosuppressive treatment with rituximab and high-dose corticosteroids. The evolution was partially favorable, because the patient already had irreversible organ damage at the time of diagnosis.