Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics

Van den Broeck F.; Heeren S.; Maes I.; Sanders M.; Cotton J.A.; Cupolillo E.; Alvarez E.; Garcia L.; Tasia M.; Marneffe A.; Dujardin J.-C.; Van der Auwera G. · Emerging Infectious Diseases (2023) · DOI: 10.3201/eid2905.221456

Resumen

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

Instituciones: Universidad Peruana Cayetano Heredia