From Womb to World: Unravelling the Microbiota′s Impact on Health and Disease

Poterico J.A.; Venkatesh B.G.; Jaramillo-Valverde L.; Sanchez C.; Alayo E.; Valdivia-Silva J.; Guio H. · International Journal of Microbiology (2026) · DOI: 10.1155/ijm/9228548

Resumen

The human body hosts an intricate array of microbial communities, outnumbering eukaryotic cells. Delving into the nuanced interplay between the microbiota and human cells is essential for comprehending health homeostasis and disease progression. Notably, the microbiota′s influence commences even before birth, sculpting immune responses and delineating susceptibility to chronic diseases in later stages of life. Throughout the course of human life, variations in microbial composition have been observed to correlate with a wide range of pathologies, prompting the development of pioneering treatments aimed at reinstating a healthier microbial balance. Within this narrative review, we expound upon the fundamental role of the microbiota in the continuum of health and disease. Our endeavour is to contribute to a nuanced comprehension of diseases and the development of targeted interventions for their judicious management. Copyright

Instituciones: Universidad San Ignacio de Loyola; Universidad Continental; Universidad de Huánuco; Universidad de Ingeniería y Tecnología