FREQUENCY OF METABOLIC SYNDROME IN PERU: A SYSTEMATIC REVIEW AND META-ANALYSIS

Vera-Ponce V.J.; Zuzunaga-Montoya F.E.; Vásquez-Romero L.E.M.; Loayza-Castro J.A.; Bustamante-Rodríguez J.C.; Sanchez-Tamay N.M.; Vigil-Ventura E.; Gutiérrez de Carrillo C.I. · Revista de la Facultad de Medicina Humana (2026) · DOI: 10.25176/rfmh.v26i1.6837

Resumen

The aim of the study was to estimate the frequency of metabolic syndrome (MetS) in the Peruvian population through a systematic review and meta-analysis, and to describe the diagnostic criteria most commonly used across studies. A systematic search was conducted in PubMed, Scopus, Web of Science, and SciELO through December 2023. Observational studies reporting the frequency of MetS in the Peruvian adult population were included. A random-effects model with logit transformation was used for the meta-analysis. Subgroup analyses by sex and meta-regression by year of data collection were performed. Eleven studies involving 14,698 participants were included. The pooled frequency of MetS was 23.84% (95% CI: 18.32-29.85%) using ATPIII criteria (8 studies; I2=97%) and 28.03% (95% CI: 18.31-38.91%) using IDF criteria (5 studies; I2=98%). Using JIS criteria, the frequency was 37.31% (95% CI: 25.80-49.59%; 4 studies), and using WHO criteria, it was 30.39% (95% CI: 3.88-67.94%; 2 studies). Higher frequency was observed in women than in men using both ATPIII (30.43% vs 16.96%) and IDF (34.85% vs 29.57%) criteria. Meta-regression showed a significant increase in frequency over time using ATPIII criteria (β=0.063; p<0.001). Approximately one in four Peruvian adults has MetS. Frequency varies according to the diagnostic criteria used and is higher in women. An increasing trend in frequency has been observed over the past two decades. The high heterogeneity observed across studies indicates that further research with standardized methodologies and nationally representative samples is required to obtain more precise estimates. Article published by the Revista de la Facultad de Medicina Humana of Universidad Ricardo Palma. It is an open access article, distributed under the terms of the Creative Commons License: Creative Commons Attribution 4.0 International, CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/), which allows non-commercial use, distribution and reproduction in any medium, provided that the original work is duly cited. For commercial use, please contact revista.medicina@urp.edu.pe

Instituciones: Universidad Continental; Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas