Factors associated with kidney graft survival in post-transplant patients at Hospital Nacional Ramiro Priale-Priale, 2004-2023

Cerrón-Ventocilla K.J.; Vía y Rada-Sáenz J.P.; Arancibia-Sedano M.S.; Arellán-Bravo L. · Acta Medica Peruana (2025) · DOI: 10.35663/amp.2025.421.3276

Resumen

Objective: To identify factors related to kidney graft survival in transplanted patients. Materials and Methods: We analyzed 34 medical records of kidney transplant patients at Ramiro Priale-Priale National Hospital between January 2004 and April 2023. To determine graft survival, the Kaplan-Meier test and Cox regression with the stepwise method were performed. Additionally, univariate, and bivariate analyses (chi-square) were conducted. Results: The mean graft survival time at the time of the study was 11.25 years, with a 95% confidence interval. The predominant cause of chronic kidney disease was high blood pressure in 85.2% patients, followed by vasculitis in 8.8%. Nearly eighty percent (79.4%) of grafts were from living donors. Most commonly used immunosuppressive treatments included tacrolimus, prednisone, and mycophenolate in 82.4% of cases. In the bivariate analysis, the only factor associated with graft loss was the time elapsed since kidney transplantation until the time of this study (p= 0.033), with a confidence interval between 1.001 and 1.034. Conclusion: Time elapsed since kidney transplantation is associated with graft survival.

Instituciones: Universidad Continental