Factors associated with HER2 positive breast cancer: Retrospective analysis of a hospital in Peru

Martínez A.; Vela-Ruiz J.M.; Rivadeneyra-Romero R.; de la Cruz-Vargas J.A.; Calle-Villavicencio A.; Pérez-Ramos C.; Sotelo M.J. · Revista Venezolana de Oncologia (2022)

Resumen

OBJECTIVE: Determine factors associated with HER2 positive breast cancer in patients treated at MariaAuxiliadora Hospital during 2016-2019. METHOD: The research is observational, retrospective, quantitative, analytical and of case and control type. 43 women diagnosed HER2 (+) 86 HER2 (-). The statistical evaluation was developed in the SPSSv.23 program, applying the Chi square test and the Odds Ratio, with a significance level 5 %. RESULTS: The mean age was 55 years; The association between HER2 positive breast cancer, age, body index mass, tumor size, histological grade and clinical stage were (OR: 0.821; 95 % CI = 0.360-1.871; P: 0.639), (OR: 0.427; 95 % CI = 0.146- 1.244; P: 0.119), (OR: 0.487; 95 % CI = 0.208-1.139; P: 0.097), (OR: 1.538; 95 % CI = 1.351-1.750; P: 0.076), (OR: 1.218; 95 % CI = 0.391 -3.798;P: 0.734) respectively. CONCLUSION: In our retrospective study, there are variables such as age, histological grade, body index mass that are not associated with HER2-positive breast cancer.