Factors Associated with Drug Consumption Without Scientific Evidence in Patients with Mild COVID-19 in Peru

Soriano-Moreno D.R.; Fernandez-Guzman D.; Sangster-Carrasco L.; Quispe-Vicuña C.; Grados-Espinoza P.; Ccami-Bernal F.; Morocho-Alburqueque N.; Coba-Villan N.; Velasquez-Fernandez R.; Nieto-Gutierrez W. · Journal of Patient Safety (2022) · DOI: 10.1097/pts.0000000000001053

Resumen

Objective This study aimed to evaluate the factors associated with the consumption of drugs without scientific evidence in patients with mild COVID-19 infection in Peru. Methods An analytical cross-sectional study was carried out including 372 adult patients with a history of mild COVID-19 disease. Factors associated with drug consumption were evaluated by Poisson regressions with robust variance adjustment using the bootstrapping resampling method. Results Seventy-two percent consumed some medication without scientific evidence, with antibiotics (71%) and ivermectin for human use (68%) being the most commonly used. Factors associated with the consumption of drugs to treat mild COVID-19 infection were thinking that the drugs are not effective (adjusted prevalence ratio, 0.55; 95% confidence interval, 0.41-0.74) and not being informed about the efficacy of the drugs (adjusted prevalence ratio, 0.48; 95% confidence interval, 0.36-0.65). Conclusions Education of the population seems to be the main factor that increases the consumption of drugs without scientific evidence in the Peruvian population to treat mild COVID-19. © Wolters Kluwer Health, Inc. All rights reserved.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad Peruana de Ciencias Aplicadas; Universidad Nacional Daniel Alcides Carrión; Universidad Nacional de San Antonio Abad del Cusco; Universidad Nacional de San Agustín de Arequipa; Universidad San Ignacio de Loyola; Universidad Nacional de Cajamarca; Universidad Peruana Unión