Ethnic Minority Participation in Clinical Trials from Latin America and the Caribbean: A Scoping Review

Herrera-Añazco P.; Benites-Meza J.K.; Caira-Chuquineyra B.; Fernandez-Guzman D.; Hernandez-Bustamante E.A.; Benites-Zapata V.A. · Journal of Immigrant and Minority Health (2024) · DOI: 10.1007/s10903-023-01578-y

Resumen

We summarize the clinical trials (CTs) main characteristics, including members of ethnic minorities from Latin America. We carried out a systematic search in six databases. We made a descriptive synthesis of CTs, summarizing the characteristics, interventions, main findings, results, and conclusions reported. 4411 studies were acquired in search strategy, leaving 24 CTs in the final selection. Of these, ten were randomized, four were non-randomized, and the remainder had other designs. Most of the studies were carried out in the population of infants and children (08), ten of the studies included only women, and two studies included men. Nine studies were conducted in Mexico, with the Mayan ethnic minority being mostly evaluated (05). In only 15 it was mentioned that their research was approved by a research ethics committee. Finally, half of the CTs reported funding from international agencies and third reported funding from government agencies. Our results show that that CTs in ethnic minorities are limited and reduced to a few native peoples of the continent. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.

Instituciones: Universidad Científica del Sur; Universidad Nacional de San Agustín de Arequipa; Universidad San Ignacio de Loyola; Universidad Privada del Norte