Effectiveness of systemic antibiotic therapy in reducing dry socket incidence after tooth extraction: A randomized controlled trial

Evelyn Paola Castillo-Quispe; Shelly Wendy Ipenza-Mejía · TUMI Oral Health (2026) · DOI: 10.64716/3f1r6h41

Resumen

Alveolar osteitis, commonly known as dry socket, is one of the most frequent postoperative complications following tooth extraction and is associated with significant patient discomfort and delayed healing. Although several preventive strategies have been proposed, the role of systemic antibiotic therapy in reducing its incidence remains controversial due to concerns about effectiveness and antimicrobial resistance. This study aimed to evaluate the effectiveness of systemic antibiotic therapy in reducing the incidence of dry socket after tooth extraction in a primary healthcare center located in northern Peru. A quantitative, longitudinal, randomized controlled trial was conducted, including a total of 120 patients undergoing tooth extraction. Clinical evaluations were performed postoperatively, and data were recorded using a standardized data collection form. The results showed that the overall incidence of dry socket varied across demographic groups, with similar proportions observed between males (27.5%) and females (26.7%). Regarding age distribution, the highest frequency was observed in patients aged 46 years and older (25.0%), followed by younger age groups. Patients receiving systemic antibiotic therapy showed a lower occurrence of dry socket compared to those who did not receive antibiotics. These findings suggest that systemic antibiotic therapy may be effective in reducing the incidence of dry socket following tooth extraction. However, its use should be carefully considered in the context of clinical indications and antimicrobial stewardship.

Instituciones: Universidad Católica Los Ángeles de Chimbote