Dipyrone anaphylaxis in a pregnant patient during labor epidural analgesia

Pilco E.Q.; Pilco J.Q.; Lozano M.C.; Castillo J.L.; Figueroa J.S.; Castillo M.C. · Revista Chilena de Anestesia (2023) · DOI: 10.25237/revchilanestv52n6-13

Resumen

Anaphylaxis is a severe systemic hypersensitivity reaction with a sudden and unpredictable onset, it presents a clinical features that severely compromises the cutaneous, respiratory and cardiovascular systems. In pregnant women, diagnosis and treatment can be difficult due to the physiological changes of pregnancy and the risk of fetal well-being. The case of a pregnant woman in labor is reported, who presented anaphylaxis after the administration of dipyrone and epidural labor analgesia. A good response to treatment with adrenaline was evidenced, with adequate recovery after the event. The patient had no history of hypersensitivity to dipyrone or other drugs, in order to identify the causative agent, a basophil activation test to dipyrone was performed, which was negative, subsequently skin tests were performed: Prick Test and intradermal test with all suspected drugs giving both positive tests to dipyrone.

Instituciones: Universidad Nacional Mayor de San Marcos