Diagnostic Role of Tomography in Addison's Disease due to Adrenal Tuberculosis: A Case Report

Quiroz-Aldave J.E.; del Carmen Durand-Vásquez M.; Gamarra-Osorio E.R.; Zavaleta-Aldave S.E.; Zavaleta-Aldave A.N.; Rodríguez-Reyna J.; Quesquén-García C.M.; Concepción-Urteaga L.A.; Pecho-Silva S.; Rodríguez-Hidalgo L.A.; Paz-Ibarra J.; Concepción-Zavaleta M.J. · Endocrine, Metabolic and Immune Disorders - Drug Targets (2025) · DOI: 10.2174/0118715303305534240709115115

Resumen

Introduction: Adrenal tuberculosis remains the main cause of primary adrenal insufficiency (PAI) in tuberculosis (TB)-prevalent regions. This case report details the presentation of PAI due to adrenal TB, where the etiological diagnosis involves Abdominal Computed Tomography (CT). Case Report: A 37-year-old Peruvian woman with a history of TB contact displayed symptoms of adrenal insufficiency. PAI diagnosis was established, and CT imaging unveiled bilateral adrenal enlargement with calcifications. Treatment with prednisone and anti-TB therapy led to symptomatic improvement. Unfortunately, she succumbed to pneumonia after ten months of follow-up. Discussion: Adrenal TB must be considered in endemic regions and in the presence of a TB history. CT serves as a valuable diagnostic tool, particularly in settings with limited resources, revealing adrenal enlargement and calcifications. Conclusion: In patients with PAI, epidemiological history of TB, and when a rapid biopsy is not feasible, CT proves to be a valuable diagnostic method.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad Científica del Sur; Universidad Nacional de Cajamarca