Diagnostic accuracy of different anthropometric indicators for detecting lipid profile alterations in the Peruvian population

Valencia J.G.; Rios-Escalante C.; Mamani-Urrutia V. · Romanian Journal of Diabetes, Nutrition and Metabolic Diseases (2024) · DOI: 10.46389/rjd-2024-1650

Resumen

Dyslipidemias are prevalent cardiovascular risk factors in Latin America. This study aimed to assess the diagnostic accuracy of anthropometric indicators in detecting lipid profile alterations in Peruvian individuals. A diagnostic test study with secondary analysis of the PERU MIGRANT study was conducted using index tests based on waist circumference and skinfold thickness. Outcomes included hypercholesterolemia, low HDL-c, elevated triglycerides, and high total cholesterol to HDL-c ratio (TC/HDL-c). Receiver operating characteristic curves and area under the curve (AUC) were assessed with optimal cutoff points determined by the Youden index, stratified by sex. A number of 972 participants were included. Waist circumference showed the highest AUC for hypercholesterolemia (0.65 in women, 0.67 in men). The waist-to-height ratio showed the highest AUC for elevated triglycerides (AUC: 0.66). For low HDL-c, waist-to-hip ratio in women (AUC: 0.62) and waist-to-height ratio in men (AUC: 0.65) performed best. Waist-to-height ratio demonstrated AUCs ≥0.70 for elevated TC/HDL-c ratio in both sexes, with waist circumference having an AUC of 0.71 in men. Waist-based tests demonstrated moderate to high diagnostic capabilities for lipid alterations, particularly for elevated TC/HDL-c ratio. Further research is needed to confirm these findings.

Instituciones: Universidad Científica del Sur; Universidad Privada del Norte