Dengue congenital as a differential diagnosis in neonates with suspected neonatal sepsis: a case report in an endemic region

Espinoza-Venegas L.A.; Samame-Talledo B.K.; Mauricio-Neyra L.G.; Pampa-Espinoza L.; Munayco-Guillén F.; Pichardo-Rodríguez R. · Boletin Medico del Hospital Infantil de Mexico (2025) · DOI: 10.24875/bmhim.24000107

Resumen

Background: A major dengue epidemic affected Peru in 2023, with more than 246,614 cases with 419 deaths and an approximate of 8,312 pregnant women affected, with risk of transmitting the virus to the fetus. Clinical case: The case of an 11-day-old newborn is reported, whose mother started dengue fever one day before delivery, who was admitted to the emer-gency room with a diagnosis of sepsis (fever, jaundice, alteration of sensorium) and a history of cesarean delivery due to acute fetal distress. RT-PCR for dengue serotype 2 was identified in both the mother and neonate, suspending antibiotics and starting controlled hydration therapy, with favorable evolution that allowed the 7 to be discharged from hospitalization. Conclusions: Congenital dengue should be suspected in any neonate whose mother presents dengue up to 10 days before delivery and who presents a clinical picture of sepsis, and we must monitor the neonate until the 12th day of life.

Instituciones: Universidad César Vallejo