Decreased C-reactive protein/lymphocyte ratio as a prognostic factor for mortality in patients with COVID-19

Enriquez A.P.S.; Vásquez-Tirado G.A.; Quispe-Castañeda C.V.; Meregildo-Rodríguez E.D.; Alva-Guarniz H. · Boletin de Malariologia y Salud Ambiental (2023) · DOI: 10.52808/bmsa.8e7.632.006

Resumen

The objective of this study was to determine that the decreased lymphocyte/C-reactive protein (L/CRP) ratio is a prognostic factor for mortality in patients with COVID-19. The research had an analytical, observational, retrospective and longitudinal cohort design carried out in 93 patients. The frequency distribution data of qualitative variables and the measures of centralization and dispersion of quantitative variables were obtained. In addition, the Chi Square (X2) test was used, therefore, the associations were considered significant if p was less than 0.05. Finally, among the qualitative variables, the relative risk of the L/CRP index with respect to the risk of mortality in COVID-19 was calculated. Afterwards, the multivariate analysis was carried out with logistic regression for the intervening variables that were significant in the bivariate analysis. In the results, of the 93 patients, it was possible to show that 44.1% died. In addition to this, it was found that age over 60 years, normal lymphocyte counts and decreased values of the L/CRP Index proved to be a risk factor for mortality in patients with COVID-19. In conclusion, the decreased L/CRP ratio is a prognostic factor for mortality in patients with COVID-19.

Instituciones: Universidad Privada Antenor Orrego; Universidad César Vallejo