Comprehensive analysis of antibiotic and heavy metal resistance, and virulence factors in Aeromonas veronii CTe-01: Implications for global antimicrobial resistance

Tataje-Lavanda L.; Ormeño-Vásquez P.; Choque-Guevara R.; Altamirano-Díaz R.; Fernández-Díaz M.; Tantaleán J.C. · Journal of King Saud University - Science (2024) · DOI: 10.1016/j.jksus.2024.103402

Resumen

Objectives: This study aimed to characterize Aeromonas veronii CTe-01 focusing on its resistance to heavy metal and antibiotics. Methods: A. veronii CTe-01 was characterized using standard microbiological and molecular techniques. Antibiotic susceptibility and heavy metal resistance were tested per standard protocols. Genomic analysis, including plasmid characterization, was conducted in silico. Results: A. veronii CTe-01 showed resistance to various heavy metals and antibiotics. Multiple resistance genes were identified, including those for beta-lactamases, heavy metal resistance, and type III secretion system components. The bacterium carries a 9 kb plasmid with repA/repB replication genes, parA/parB partitioning genes, and a type II toxin-antitoxin system for stability. Conclusions: A. veronii CTe-01 is a genetic reservoir for antibiotic resistance, heavy metal resistance genes, and virulence factors. The study offers insights into its dual role as a pathogen and heavy metal remediator in aquatic environments.

Instituciones: Universidad Nacional San Luis Gonzaga