Comparison of haemoglobin assessments with Hemo Control and Sysmex XN-1000™ in high altitude resident patients (Huancayo – Peru)

Solis-Camarena R.; Soto-Agreda Y.; Quiroz-Cornejo K.V.; Arellano-Salazar M.P.; Haider T.J.; Zutta B.; Samillan V.J. · Semergen (2026) · DOI: 10.1016/j.semerg.2026.102702

Resumen

Objectives The accessibility of automated haematology analysers is frequently limited to clinical centres and thus not available for a significant number of patients, especially those living in remote areas (e.g. high-altitude regions), the objective of the present study was to compare a portable and easy to handle hemoglobinometer (HM) with an automated haematology analyser (HA) as a reference standard for their agreement in measuring the Hb concentration in high altitude resident patients. Methods We applied two different devices (HA: Sysmex XN-1000™ analyses, HM: Hemo Control hemoglobinometer, EKF Diagnostics) to determine the Hb concentration in 520 venous blood samples, which were obtained from patients, who were admitted to the Clinical Laboratory of Ramiro Priale-Essalud National Hospital (Huancayo, Peru, 3259 m.a.s.l.). The agreement between the two methods was evaluated by applying the Bland–Altman method and calculating the bias and the precision between the two devices. Results The Hb concentrations (mean ± SD g/dL) of measured blood samples were 14.6 ± 2.8 g/dL and 14.7 ± 2.8 g/dL for the HA and for HM respectively. The bias (mean difference ± SD g/dL, HA − HM) was −0.080 ± 0.5428 g/dL and the agreement limits were −1.091 to 0.930 g/dL. Conclusions The Hemo Control is a portable, easy to handle and a comparatively accurate device with sufficient agreement with the reference standard to determine Hb concentration in patients living in remote regions without access to automated haematology analysers.

Instituciones: Universidad Le Cordon Bleu; Universidad Privada del Norte