Comparison of Bactericidal Properties of ZnO Nanoparticles Obtained By Two Synthesis Methods

Cordova S.; Guzman M.; Galarreta B.C.; Hernandez Y.; Chumpitaz O.; Flores S.; Malet L.; Godet S. · World Congress on Recent Advances in Nanotechnology (2024) · DOI: 10.11159/icnnfc24.129

Resumen

The potential bactericidal properties of nanosized zinc oxide (ZnO) make this semiconductor suitable for medical and pharmaceutical applications. In this article we present two methods of synthesis of ZnO nanoparticles (Nps-ZnO): chemical precipitation and solution combustion synthesis. The synthesized nanopowders were characterized with Scanning Electron Microscopy-Energy Dispersive X-Ray Spectroscopy (SEM-EDS), X-ray Diffraction (XRD) and Transmission Electron Microscopy (TEM). The EDS analysis indicate a Zn:O atomic ratio of 0.81 and 1.36, for the chemical precipitation and solution combustion synthesis, respectively. The XRD results confirm that Nps-ZnO obtained by both methods show a hexagonal arrangement (Wurtzite). TEM images show nanoparticles with mean diameters between 15.5 ± 6.8 nm and 73.4 ± 6.0 nm. Finally, the Kirby−Bauer disk diffusion method for the determination of antibacterial activity shows that Escherichia coli was more sensitive to the antimicrobial action of Nps-ZnO obtained by chemical precipitation than the Bacillus Subtilis bacteria.

Instituciones: Pontificia Universidad Católica del Perú