CLONAL DIVERSITY OF CARBAPENEMASE-PRODUCING Pseudomonas aeruginosa ISOLATED FROM CLINICAL SAMPLES IN A THIRD LEVEL HOSPITAL IN PERU

Salvador-Lujan G.; Cruz-Pio L.E.; Calla H.; Rivera-Asencios D.; Solís-Cayo L.; García-De-la-guarda R. · Revista Peruana de Medicina Experimental y Salud Publica (2025) · DOI: 10.17843/rpmesp.2025.421.13818

Resumen

Pseudomonas aeruginosa is an opportunistic pathogen associated with health care infections, it has high levels of antimicrobial resistance and is associated with hospital outbreaks. Early outbreak detection is a usual problem in hospitals, therefore, this study aimed to assess the clonal relationship of carbapenemase-producing P. aeruginosa in a tertiary hospital in Lima, Peru. Twenty-four metallo β-lactamase-producing P. aeruginosa strains isolated from hospitalized patients were collected. The clonal relation was determined using the REP-PCR technique. REP-PCR band profiles were normalized, analyzed and combined using BioNumerics version 7.6 software. Molecular identification showed 19 different profiles and four clonal groups. We determined polyclonality among isolates. We did not find clonal dissemination among the metallo-β-lactamase-producing P. aeruginosa strains circulating in the hospital.

Instituciones: Universidad Nacional Mayor de San Marcos