Clinical characteristics, comorbidity, and laboratory variables associated with hospitalization and mortality in older people with Covid-19: A systematic review

Aguilar M.A.C.; Aguilar V.J.C.; Aravena C.C.A.; Yáñez-Yáñez R.; Leitón-Espinoza Z.E.; Cigarroa I. · Salud Uninorte (2022) · DOI: 10.14482/sun.38.3.616.24

Resumen

Objective: To characterize clinical indicators, comorbidity and laboratory variables associated with hospitalization and mortality in older people with Covid-19. Materials and methods: A systematic review was carried out in accordance with the PRIS-MA statement, in the Medline/Pubmed, Science databases. Direct and WOS, in which specific search strategies were applied to articles and studies that were published from the period of time between January 1, 2020 and November 26, 2020. Results: 28 articles were identified that met the the selection criteria, with a sum of the sample size of the included studies of 581,319 subjects (55.1% women). Of the factors analyzed, optimal functional status, female gender, lymphocyte count, curative use of anti-coagulants, and serum albumin levels have been associated with a better clinical prognosis in adults older than 65 years. Conclusions: Clinical characteristics, comorbidity and laboratory variables associated with hospitalization and morbidity were found.

Instituciones: Universidad Nacional de Trujillo