Chronic kidney disease due to focal and segmental glomerulosclerosis associated with HIV in an adolescent

Arellan-Bravo L.; Tovar A.R.C.; Guerra V.E.Z.; Vera-Gonzales G.D.; Hurtado-Alegre J.L. · Anales de la Facultad de Medicina (2024) · DOI: 10.15381/anales.v85i3.27916

Resumen

The most frequent glomerular diseases associated with nephrotic syndrome (NS) in adults are membranous glomerulonephritis (MG) and focal segmental glomerulosclerosis (FSGS), related to HIV and infrequent in adolescents. Our objective is to describe a case of FSGS associated with HIV and the coexistence of amyloidosis and to demonstrate its improvement with highly active antiretroviral therapy (HAART). A 14-yearold female adolescent was admitted to the Emergency Department for 1 week of illness after presenting oliguria and anasarca; a month later she was readmitted due to exacerbation of edematous symptoms and was diagnosed with juvenile rheumatoid arthritis (JRA). A renal biopsy was performed and secondarism tests were positive for HIV. In conclusion, it is unusual to find this glomerulopathy in an adolescent, so it is necessary to consider initially the presence of secondary disease in adolescents, showing the improvement of FSGS associated with HIV infection with HAART treatment.

Instituciones: Universidad Continental