Chorioretinitis in a patient with disseminated histoplasmosis and systemic lupus erythematosus

Chagua D.C.; López Fuentes M.; Guzmán J.V.; Álvarez B.Y. · Anales de la Facultad de Medicina (2024) · DOI: 10.15381/anales.v85i2.25891

Resumen

Disseminated histoplasmosis (HD) is a systemic fungal infection, where Histoplasma capsulatum spreads from the lungs to different organs via the blood. It occurs mainly in severely immunocompromised patients who come from or have visited endemic regions. We report the case of a 39-year-old woman with Systemic Lupus Erythematosus (SLE) of 11 years of evolution, treated with immunosuppressants and corticosteroids, who developed the disseminated form of the disease (lungs, skin, tongue, chorioretina). The association SLE and HD has been described, being the course variable depending on the degree of immunosuppression. In the presence of chorioretinitis with other localized systemic manifestations in patients with SLE or other autoimmune diseases, HD should be highly suspected in the differential diagnosis.