CHAR ACTERISTICS OF COVID-19-ASSOCIATED MULTISYSTEMIC INFLAMMATORY SYNDROME IN CHILDREN TREATED IN A PERUVIAN HOSPITAL, 2020-2022

Atamari-Anahui N.; Huby-Muñoz C.; Peña-Coello C.; Guillen-Buleje D.; Gomez-Martinez L.; Nuñez-Paucar H.; Zamudio-Aquise M.; Bernal-Mancilla R.; De Coll-Vela L.; Orellana-Siuce C.; Candela-Herrera J. · Revista Peruana de Medicina Experimental y Salud Publica (2024) · DOI: 10.17843/rpmesp.2024.413.13736

Resumen

This study aimed to describe the characteristics of multisystemic inflammatory syndrome associated with COVID-19 (MIS-C) in the first three years of the pandemic in children in a pediatric hospital in Peru. We conducted an observational, descriptive study with data from 73 patients and described the clinical and laboratory characteristics, treatment and complications according to the wave of the pandemic and whether they had shock. The median age was 6 years, gastrointestinal and mucocutaneous manifestations were frequent in the three waves. Kawasaki disease-like phenotype was present in 34 (46.6%) patients and 21 (28.8%) patients developed shock. The most commonly used treatment was immunoglobulin (95.9%), followed by acetylsalicylic acid (94.5%) and corticosteroid (86.3%). Five (7%) patients had coronary aneu-rysm and 17 (23.3%) were admitted to the intensive care unit (ICU). Patients with shock had greater labora-torial alteration and need for mechanical ventilation. In conclusion, MIS-C has decreased in the first three years of the pandemic, possibly due to COVID-19 vaccination in children.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad de San Martín de Porres; Universidad San Ignacio de Loyola