ASSOCIATION BETWEEN OVERWEIGHT/OBESITY AND MULTIDRUG-RESISTANT TUBERCULOSIS

Peinado J.; Lecca L.; Jiménez J.; Calderón R.; Yataco R.; Becerra M.; Murray M. · Revista Peruana de Medicina Experimental y Salud Publica (2023) · DOI: 10.17843/rpmesp.2023.401.12138

Resumen

Objective. To evaluate the association between overweight/obesity and multidrug resistance in patients with and without a history of tuberculosis treatment. Materials and methods. Cross-sectional study of secondary data from a tuberculosis cohort, which included anthropometric and drug-sensitivity testing data at the baseline visit of patients with and without previous tuberculosis treatment. Results. We evaluated 3,734 new cases and 766 with a history of having received treatment for tuberculosis. Overweight/ obesity was not associated with multidrug resistance in patients with a history of tuberculosis treatment, with a prevalence ratio of 0.97 and a 95% confidence interval of 0.68-1.38. Conclusions. Overweight/ obesity is not associated with multidrug resistance in tuberculosis. Overweight/obesity is a dynamic pro-cess that may influence the relationship between the immune system and the metabolic system.

Instituciones: Universidad Peruana de Ciencias Aplicadas