Antibacterial Activity of Vaccinium floribundum and Bacharis linearifolia Extracts against Escherichia coli

León J.R.H.; Serrano G.C.; Mora D.S.; Joaquin J.W.S.; Siesquen J.S. · Revista Cubana de Medicina Militar (2025)

Resumen

Introduction: Urinary tract infections, primarily caused by the bacterium Escherichia coli, have shown increasing resistance to traditional antibacterial treatments. Given this problem, the use of natural compounds, such as those found in Vaccinium floribundum (Mortiño) and Baccharis linearifolia (Sacha Thola), is proposed as a therapeutic alternative. Objective: To evaluate the antibacterial activity of hydroalcoholic extracts of Vaccinium floribundum and Baccharis linearifolia against Escherichia coli ATCC 25922. Methods: An experimental study was conducted using hydroalcoholic extracts obtained from the leaves and fruits of V. floribundum and the leaves of B. linearifolia. Antibacterial activity was determined using the agar diffusion method at different concentrations. Inhibition zones were measured and statistically analyzed using ANOVA. Results: Both extracts showed antibacterial activity against Escherichia coli, with inhibition zones ranging from 6.0 mm to 10.9 mm. Intermediate concentrations (2.5%) generated the largest zones. No statistically significant differences (p > 0.05) were observed between treatments. Conclusions: The extracts evaluated showed an inhibitory effect on Escherichia coli, especially at intermediate concentrations. Further studies are recommended to optimize the extraction process and evaluate its therapeutic application.

Instituciones: Universidad María Auxiliadora