Angioimmunoblastic T-cell lymphoma as a mimic of systemic lupus erythematosus

Vilcapuma W.J.S.; Patrón-Ordóñez G.; Sánchez G.A.C. · Anales de la Facultad de Medicina (2022) · DOI: 10.15381/anales.v83i4.23827

Resumen

Angioimmunoblastic T-cell lymphoma (LAIT) is a rare non-Hodgkin lymphoma, can mimic autoimmune diseases, and has a poor prognosis. We present the case of a 36-year-old woman with a 3-year illness characterized by fever, arthralgia and weight loss. She was initially diagnosed as systemic lupus erythematosus, but finding no improvement with treatment, her diagnosis was reconsidered. In a new hospitalization, multiple lymph nodes were identified. They performed a biopsy of one of the adenopathies, the pathology was compatible with LAIT. Three chemotherapy sessions were indicated, however, she developed multiple organ failure with a fatal outcome. LAIT is a diagnostic challenge because it can mimic several autoimmune pathologies. Its suspicion and ruling out is very important to initiate early treatment that improves patient survival.

Instituciones: Universidad Nacional Mayor de San Marcos; Universidad Ricardo Palma