Advanced penile lymphoma: Case report and review of the literature

Arambulo S.; Calle A.; Vela J.; Sotelo M. · Journal of Cancer Research and Therapeutics (2023) · DOI: 10.4103/jcrt.jcrt_593_21

Resumen

Primary penile lymphomas are extremely rare. They are aggressive neoplasms that can present as double-or triple-hit lymphomas, and because the associate with a high risk of central nervous system dissemination, treatment consists of high-dose chemotherapy regimens plus intrathecal prophylaxis. Pathology can be confused with squamous cell carcinoma of the penis, leading to inappropriate treatments and unnecessary amputations. We report the case of a patient diagnosed with clinical Stage IV penile non-Hodgkin lymphoma that was treated with a complete and durable response. In addition, we review the available literature on penile lymphoma.